ChemicalBook >> CAS DataBase List >>2-(2-Aminoethyl)isothiourea dihydrobromide
2-(2-Aminoethyl)isothiourea dihydrobromide
- CAS No.
- 56-10-0
- Chemical Name:
- 2-(2-Aminoethyl)isothiourea dihydrobromide
- Synonyms
- AET;ixecur;usafxr-31;surrectan;ANTIRADON;NSC 22877;AET, DiHBr;AET-NSC-22877;AET, DIHYDROBROMIDE;IFLAB-BB F0861-0023
- CBNumber:
- CB9753183
- Molecular Formula:
- C3H11Br2N3S
- Molecular Weight:
- 281.01
- MDL Number:
- MFCD00037011
- MOL File:
- 56-10-0.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:03
| Melting point | 190-196 °C(lit.) |
|---|---|
| Density | 1.94 g/cm3 |
| storage temp. | Store below +30°C. |
| solubility | 50g/l |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | almost transparency |
| Merck | 14,178 |
| BRN | 3911163 |
| CAS DataBase Reference | 56-10-0(CAS DataBase Reference) |
| FDA UNII | 03K18418PY |
| EPA Substance Registry System | Carbamimidothioic acid, 2-aminoethyl ester, dihydrobromide (56-10-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36/37-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UM0175000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2930 90 98 | |||||||||
| Toxicity | LD50 in mice (mg/kg): 100 i.v., 280 s.c., 480 i.p., 1600 orally (Pospisil) | |||||||||
| NFPA 704 |
|
2-(2-Aminoethyl)isothiourea dihydrobromide price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A5879 | 2-(2-Aminoethyl)isothiourea dihydrobromide | 56-10-0 | 25g | $98.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20064 | S-(2-Aminoethyl)thiouronium bromide hydrobromide for synthesis | 56-10-0 | 10g | $68.2 | 2024-03-01 | Buy |
| TCI Chemical | A1078 | S-(2-Aminoethyl)isothiouronium Bromide Hydrobromide >98.0%(T) | 56-10-0 | 25g | $55 | 2024-03-01 | Buy |
| Alfa Aesar | L14232 | S-(2-Aminoethyl)isothiourea dihydrobromide, 98% | 56-10-0 | 5g | $21.65 | 2024-03-01 | Buy |
| Alfa Aesar | L14232 | S-(2-Aminoethyl)isothiourea dihydrobromide, 98% | 56-10-0 | 25g | $56.65 | 2024-03-01 | Buy |
2-(2-Aminoethyl)isothiourea dihydrobromide Chemical Properties,Uses,Production
?Synthesis
Ethylamine thiourea is synthesized by using cycloethylamine, hydrobromic acid and thiourea as raw materials: firstly, thiourea is mixed with hydrogen bromide acid, and cycloethylamine is added dropwise at a temperature below 150 °C. After the reaction is completed, add activated carbon to filter, and then reduce Dehydration under pressure, crystals are precipitated when the temperature is below 50°C, filtered, and washed twice with absolute ethanol.
Description
S-
Chemical Properties
Crystals, hygroscopic.
Uses
NOS inhibitor
Uses
Has radioprotective activity against x-rays.
Uses
2-(2-Aminoethyl)isothiourea dihydrobromide inhibits nitric oxide synthase (NOS).
Purification Methods
Crystallise the salt from absolute EtOH/ethyl acetate or MeOH. Store dry as it is hygroscopic in a humid atmosphere. It is a radioprotective agent. When refluxed in EtOH for 16hours or H2O for 30minutes, it decomposes to 2-amino-4(5H)-thiazoline hydrobromide which on recrystallisation from isoPrOH/EtOAc has m 175-176o [Doherty et al. J Am Chem Soc 79 5667 1957].
References
[1]. garvey ep, oplinger ja, tanoury gj, et al. potent and selective inhibition of human nitric oxide synthases. inhibition by non-amino acid isothioureas. j biol chem. 1994 oct 28;269(43):26669-76.
2-(2-Aminoethyl)isothiourea dihydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 152)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6709 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28557 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
View Lastest Price from 2-(2-Aminoethyl)isothiourea dihydrobromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-28 | 2-(2-Aminoethyl)isothiourea dihydrobromide USP/EP/BP
56-10-0
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2019-07-06 | 2-(2-Aminoethyl)isothiourea dihydrobromide
56-10-0
|
US $100.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co |
-
- 2-(2-Aminoethyl)isothiourea dihydrobromide USP/EP/BP
56-10-0
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- 2-(2-Aminoethyl)isothiourea dihydrobromide
56-10-0
- US $100.00 / KG
- 99%
- Career Henan Chemical Co
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AET
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